【摘要】 目的:探讨鳞癌抗原(SCC-Ag)在宫颈病变中的诊断价值。方法:回顾性分析116例宫颈病变患者的临床资料。采用化学发光法检测患者血清SCC-Ag水平,比较不同临床分期患者的SCC-Ag水平,统计患者手术前后的SCC-Ag水平。结果:早期宫颈癌患者SCCAg水平明显高于宫颈上皮内瘤变者,宫颈癌Ⅱa期患者的SCC-Ag水平明显高于宫颈癌Ⅰ期者,差异均有统计学意义(P<0.05);患者手术后SCC-Ag水平均明显低与手术前,差异有统计学意义(P<0.05),其中宫颈癌Ⅱa期患者SCC-Ag水平降低最为明显,其次为宫颈癌Ⅰ期、宫颈上皮内瘤变者。结论:SCC-Ag是重要的宫颈癌肿瘤标志物之一,可作为宫颈癌前病变和早期宫颈癌诊断指标。更多还原

【Abstract】 Objective: To investigate clinical values of squamous cell carcinoma antigen( SCC-Ag) in treatment of cervical lesions. Methods: The clinical data of a total of 116 patients with cervical lesions were retrospectively analyzed. All patients were detected by chemiluminescence method to obtain the SCC-A levels. The SCC-Ag levels of different clinical stages were compared and those before and after the surgery were statistically analyzed. Results: The SCC-Ag levels of the early cervical cancer patients were significantly higher than those of the ones,the SCC-Ag levels in the patients with stage IIa of cervical cancer were significantly higher than those of stage I of cervical cancer,and the differences were statistically significant( P< 0.05). Further,the SCC-Ag levels after the surgery were significantly lower than those before the surgery,and the differences were statistically significant( P < 0. 05). Among which,the patients with the stage IIa of cervical cancer had the greatest SCC-Ag level decline,followed by those with stage I of cervical cancer,and cervical intraepithelial neoplasia. Conclusions: SCC-Ag is one of the important tumor markers of cervical cancer and can be used as an diagnosis indicator of cervical precancerous lesions and early cervical cancer.更多还原