Liver fibrosis is a pathophysiological process in response to a host's inflammatory response,and various pathogenic factors result in abnormal tissue hyperplasia.As a consequence of chronic tissue damage,stellate cells(SCs)and extracellular matrix-producing cells undergo activation,and this process constitutes a key portion of fibrogenesis.Current understanding of the pathophysiology of liver fibrogenesis is presented here with a special emphasis on oxidative free radicals.Reactive oxygen species both parti...
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