Adoptive transfer of DCs from mice infected with Schistosoma japonicum inhibits mucus secretion of OVA-induced allergic asthma by regulating IL-13 production
Objective To examine the inhibitory effect of dendritic cells(DC)from mice infected with Schistosoma japonicum on allergic asthma and their regulation of IL-13 production. Methods DCs were isolated from the spleen of mice infected with S.japonicumusing MACS and were adoptively transferred to BALB/c mice.Allergic asthma was then induced with OVA.Normal mice and untreated mice with induced asthma served as controls.Four weeks later,the lungs were removed from the groups of mice.Total RNA was extracted for qRT...