【摘要】 目的观察泪道探通术治疗先天性泪道阻塞的临床效果。方法本研究纳入2014年1月至2017年1月在内蒙古自治区包头市中心医院眼科就诊的先天性泪道阻塞的患者76例(140只眼)的临床资料。采用数字表法将全部患者随机分为两组,其中,观察组为38例,对照组为38例。对照组患者实施常规药物治疗,观察组患者均行泪道探通术。针对两种治疗方案的近期疗效和远期效果进行比较。评价近期疗效的指标主要包括治疗的有效程度和泪道功能恢复正常的时间;评价远期效果的指标主要包括患者术后并发症的发生情况和疾病复发的情况。治疗疗效按照显效、有效及无效分为三级。观察组与对照组的疗效、并发症总发生率及总复发率的描述采用例数和百分比,两组的有效率比较采用χ~2检验。泪道恢复时间的描述采用(±s)表示,两组泪道恢复时间的比较采用t检验。结果观察组患者显效17例、有效19例及无效2例,治疗有效率为94.74%;对照组患者显效14例、有效17例及无效7例,治疗有效率为81.09%。将两组的有效程度进行比较,差异有统计学意义(χ~2=4.41,P<0.05)。对照组患者泪道恢复正常的平均时间为(5.65±1.25)d,观察组患者泪道恢复正常的平均时间为(2.64±0.97)d。将两组患者的恢复时间进行比较,差异有统计学意义(t=-12.51,P<0.05)。将发生假道形成、皮下水肿及感染撕裂等并发症的患者数据进行统计,对照组的并发症总发生率与疾病复发率均高于观察组,差异有统计学意义(χ~2=7.26,7.24;P<0.05)。结论泪道探通术效果显著,能够降低泪道阻塞性疾病术后并发症的发生率及疾病复发的几率,有益于患者病情的恢复及疾病的预后改善。可作为治疗先天性泪道阻塞性疾病的有效手段。更多还原

【Abstract】 Objective To investigate the clinical effect and influence of probing of lacrimal passage in congenital obstruction of lacrimal duct. Methods The clinical data of 76 patients( 140 eyes) with congenital obstruction of lacrimal duct from January 2014 to January 2017 in the Inner Mongolia Autonomous Region Baotou Central Hospital were included in this study. According to the order of admission,all the patients were randomly divided into two groups,of which 38 cases were in the observation group and 38 cases in the control group. The control group received routine medication,and the observation group received lacrimal probing. The short-term and long-term effects of the two treatment regimens were compared. The short-term efficacy mainly includes the effective degree of treatment and the time of lacrimal passage function returning to normal. The long term effect mainly deals with the occurrence of postoperative complications and the recurrence of the disease. The curative effect is divided into three grades according to obvious effect,effectiveness and ineffectiveness, the observation group and the control group’ s curative effect, the complication total occurrence rate and the total recurrence rate description,uses the case number and the percentage,the two groups’ efficiency comparison uses the χ~2test. The time of lacrimal passage recovery was described by( ±s) and the two groups were compared with the recovery time of lacrimal passage by t-test.Results Patients in the observation group were markedly effective in 17 cases,effective in 19 cases and ineffective in 2 cases,the effective rate was 94. 74%; the control group patients markedly effective in14 cases,effective in 17 cases and ineffective in 7 cases,the effective rate was 81. 09%. The difference between the two groups was statistically significant( χ~2= 4.41,P< 0.05). In the control group,the average time of lacrimal passage was( 5.65 ±1.25) days,and the average time of lacrimal passage in the observation group was( 2. 64 ± 0. 97) days. The recovery time of the two groups was compared,the difference was statistically significant( t =-12.51,P<0.05). The patient data form,via subcutaneous edema and infection complications such as tear statistics,the total occurrence of complications of the control group the recurrence rate and disease rate were higher than the observation group,the difference was statistically significant( χ~2=7.26,7. 24; P < 0. 05). Conclusion The effect of lacrimal passage exploration is significant,which can reduce the incidence of postoperative complications and the probability of disease recurrence. It is beneficial to the recovery of the patient’s condition and the improvement of the prognosis of the disease. It can be used as an effective treatment for congenital obstruction of lacrimal duct.更多还原