Cinacalcet hydrochloride is the first calcimimetic to decrease over secretion of parathyroid hormone,and help to reduce the concentrations of serum calcium and phosphorus.In clinical practice,cinacalcet can be used to cure secondary hyperparathyroidism to chronic kidney disease,hypercalcemia of primary hyperparathyroidism and persistent hyperparathyroidism in renal transplant patients.This review mainly summarizes the basic profile and clinical application of cinacalcet hydrochloride with the hope to help i...