【摘要】 目的分析保山市美沙酮维持治疗吸毒人群HCV感染状况及其影响因素。方法 2015年7月采用抽样调查的方法对保山市MMT吸毒人员进行问卷调查和血清学检测,调查问卷由中国疾病预防控制中心统一设计,内容包括调查对象的人口学基本信息、丙肝知晓率、吸毒方式、吸毒年龄、接受干预等情况。同时抽取5m L静脉血进行HCV抗体检测。使用EpiData 3.0建立数据库和SPSS 19.0软件包进行数据处理和统计分析。结果 MMT吸毒人群HCV感染率55.50%(222/400),HCV总知晓率为62.50%(250/400);HCV感染者和非感染者丙肝知晓率分别为70.27%(156/222)和52.81%(94/178),差异有统计学意义(χ~2=12.852,P<0.01);非条件logistic回归分析显示,未婚(OR=5.539,P=0.029,95%CI:1.191~25.745)、知晓丙肝(OR=2.266,P=0.033,95%CI:1.070~4.802)和首次吸毒年龄≥30岁(OR=0.467,P=0.002,95%CI:0.287~0.760)是美沙酮维持治疗吸毒人群丙肝感染的影响因素。结论保山市MMT吸毒人群HCV感染比较高,对未婚、丙肝知晓率低和首次吸毒年龄小于30岁的吸毒者应加强健康教育和干预,预防感染HCV。更多还原

【Abstract】 Objective Analysis on the infected status and influencing factors of HCV infection among drug users in methadone maintenance treatment in Baoshan City.Methods Questionnaire investigation and serological detection were carried out on the drug users in MMT in Baoshan city by sampling survey in July 2015.Questionnaire was designed by China center for disease control and prevention,which including the survey of the basic demographic information,hepatitis C awareness rate, the way of drug use, accepted the intervention and so on.Meanwhile,5 ml venous blood were taken for HCV antibody detection.Database was established by the EpiData3.0 software, and the SPSS 19.0 software was used to process and analyze data.Results The HCV infection rate was 55.50%( 222 /400) , the total awareness rate was 62.50% ( 250 /400).The awareness rate of HCV infected and non infected were 70.27% ( 156 /222 ) and 52.81% ( 94 /178 ) separately, there was significant difference ( χ~2 = 12.852,P < 0.01).Non conditional logistic regression analysis showed that,unmarried( OR = 5.539,P = 0.029, 95% CI: 1.191 ～ 25.745) , awareness of hepatitis C( OR = 2.266,P = 0.033, 95%CI: 1.070 ～ 4.802) and the first drug use age is greater than or equal to 30 years old ( OR = 0.467,P = 0.002, 95% CI: 0.287 ～ 0.760) were the influence factors of HCV infection among drug users in MMT.Conclusion The HCV infection rate of drug users in MMT in Baoshan city was higher, and the drug users who are unmarried,hepatitis C awareness rate is low and the first drug age less than 30 should be strengthened in health education and behavior intervention for prevention HCV infection.更多还原