【摘要】 目的探讨皮椎体成形术(PVP)治疗脊椎压缩性骨折的临床效果。方法选取2013年1月~2016年6月我院收治的46例脊椎压缩性骨折患者作为研究对象,使用随机分配的方式分为观察组和对照组,每组各23例。对照组患者实施经皮椎体后凸成形术(PKP)治疗,观察组患者实施经皮椎体成形术(PVP)治疗。比较观察组和对照组患者的VAS评分情况;术前和手术结束的次日对患者的疼痛视觉水平进行评分,术前、术后第1天和术后1年嘱患者进行X线片检查,测量椎体的高度变化,根据DR片的结果计算出椎体的实际高度;按照X线片的检测结果来判断相邻椎体骨折发生率和骨水泥渗漏的程度。结果治疗后两组患者的VAS评分均显著下降,患者疼痛明显缓解,但两组比较差异无统计学意义(P>0.05);观察组患者的手术所用时间明显短于对照组,且骨水泥注入量明显多于对照组患者,差异有统计学意义(P<0.05);观察组患者骨水泥渗漏率高于对照组,但差异无统计学意义(P>0.05);术后1年回访丢失椎体高度观察组显著低于对照组,差异有统计学意义(P<0.05);两组患者在术后伤椎都有增高现象,观察组明显低于対照组,差异有统计学意义(P<0.05)。结论对脊椎压缩性骨折患者实施经皮椎体成形术,有着显著的临床效果,减少了术后并发症的发生率,手术操作简便,值得临床推广。更多还原

【Abstract】 Objective To investigate the clinical effect of percutaneous vertebroplasty(PVP) in the treatment of vertebral compression fracture.Methods A total of 46 patients with vertebral compression fracture in our hospital from January 2013 to June 2016 were enrolled and evenly divided into observation group and control group in random.In the control group,percutaneouskyphoplasty(PKP) was used,and PVP was performed in the observation group.The visual analogue scale(VAS) score between the two groups were compared.The pain VAS scores before and first day after surgery were calculated.X-ray for patients was required before,first day and first year after surgery in order to measure the height changes of the vertebral body.The actual height of the vertebral body was deduced based on DR.According to the outcomes of X-ray,the incidence of adjacent vertebral fracture and the degree of bone cement leakage were determined.Results After therapy,the VAS scores in the two groups decreased significantly,and the pain relief was obvious,but there was no significant difference between the two groups(P>0.05).The time of operation in the observation group was greatly shorter than that in the control group,and the volume of cement injection was significantly larger than the control group,with significiant differences(P<0.05).The rate of bone cement leakage in the observation group was higher than that in the control group,but there was no significant difference(P>0.05).During one-year follow up visits after operation,the loss of the height of vertebral body was significantly lower than that in the control group(P<0.05).There was an increase in injured vertebrae after surgeries,which was significantly lower in the observation group than the control group,with significiant difference(P<0.05).Conclusion Percutaneous vertebroplasty for the patients with vertebral compression fractures have a remarkable clinical effect,reduce the incidence of postoperative complications,and the operation is simple,which is worthy of clinical promotion.更多还原