【摘要】 T2DM患者较正常人群易合并慢性肾脏病（CKD）。上海市区≥30岁T2DM患者CKD患病率可达63.9%^[1]。2015年美国肾脏数据系统^[2]显示,在引起终末期肾脏病（ESRD）的主因中,糖尿病约占44%。合并CKD的T2DM患者,由于血糖稳态和降糖药物代谢发生改变,低血糖风险更高,血糖管理更加复杂。本文综合了内分泌专家和肾内科专家的建议,对T2DM合并CKD患者在使用胰岛素上的临床经验进行汇总,并提出临床指导建议。更多还原

【Abstract】 The prevalence of chronic kidney diseases(CKD)is higher in patients with type 2 diabetes mellitus(T2DM)than in general population.In Shanghai city,the prevalence of CKD even reaches 63.9% in patients with T2DM more than 30 years old.Data from United States Renal Data System 2015 showed that 44% of ESRD were caused by diabetes.In patients with T2DM and CKD,the blood glucose management is complicated,and the hypoglycemic risk is high because of the glucose homeostasis changes and altered drug metabolism.Therefore,the current experts opinion,which integrates the recommendations and experiences of endocrinologists and nephrologists,aims to facilitate the appropriate insulin treatment in patients with T2DM and CKD in clinical practice.更多还原