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脑膜血管周细胞瘤的诊断及治疗(附8例分析)

Diagnosis and treatment of meningeal hemangiopericytomas(report of 8 cases)

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【作者】 唐玺和唐秀文蓝胜勇肖泉庞刚钟书徐柯贝徐鹏

【Author】 TANG Xi-he;TANG Xiu-wen;LAN Sheng-yong;XIAO Quan;PANG Gang;ZHONG Shu;XU Ke-bei;XU Peng;Department of Neurosurgery, People’s Hospital, Guangxi Zhuang Autonomous Region;

【机构】 广西壮族自治区人民医院神经外科

【摘要】 目的探讨脑膜血管周细胞瘤的诊断及治疗方法,以提高对该病的诊治水平。方法回顾性分析2010年1月至2016年11月收治的8例脑膜血管周细胞瘤的临床资料。结果肿瘤全切除7例,次全切除1例。术后病理检查光镜下可见瘤内血供丰富,瘤细胞弥漫生长,多梭形,染色质中等密度,核仁不明显,无脑膜瘤特异性的核仁假包涵体。免疫组化染色:8例EMA均阴性,8例Vimentin均阳性,6例CD34阳性,5例Bcl-2阳性,3例CD99阳性,8例STAT6均阳性。术后随访2~85个月,平均40.5月。术后未放疗的2例分别于术后3、60个月复发,并再次行手术切除;术后放疗的6例无复发。结论脑膜血管周细胞瘤需与脑膜瘤鉴别,首选手术切除,术后放疗可以降低复发率。

【Abstract】 ObjectiveTo enhance the levels of diagnosis and treatment of meningeal hemangiopericytomas which is an uncommondisease.MethodsThe clinical data of 8 patients with meningeal hemangiopericytomases were analyzed retrospectively, including theclinical manifestations, imaging features and postoperative pathological data.ResultsThe meningeal hemangiopericytomases weredefinitely diagnoses by the postoperative pathological examination but not by preoperative images examination. It was seenintraoperatively that the tumors appeared pale and the tumourous parenchyma was hard and tough. Of 8 patients with meningealhemangiopericytomases, 7 received total resection of the tumors and 1 subtotal.ConclusionThe differential diagnoses of the meningealhemangiopericytomas and meninginoma should be made. The surgical resection followed by radiotherapy can reduce meningealhemangiopericytomas recurrence.

  • 【文献出处】 中国临床神经外科杂志 ,Chinese Journal of Clinical Neurosurgery , 编辑部邮箱 ,2017年12期
  • 【分类号】R739.45
  • 【被引频次】3
  • 【下载频次】108
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