【摘要】 目的探讨妊娠合并梅毒的不良妊娠结局及其影响因素。方法收集2015年1月1日-2015年7月31日在某医院分娩的91例妊娠合并梅毒患者的临床资料,对其一般人口学特征、产科特征和临床特征等变量进行单因素分析和多因素分析。结果单因素分析结果显示,妊娠合并梅毒患者的年龄、母亲梅毒快速血浆反应素试验滴度和是否进行抗梅毒治疗与不良妊娠结局的发生有关。多因素分析的结果显示,妊娠合并梅毒患者的母亲梅毒快速血浆反应素试验滴度(OR=4.388,P=0.017)和是否进行抗梅毒治疗(OR=0.064,P=0.001)与不良妊娠结局相关。结论妊娠合并梅毒患者的母亲梅毒快速血浆反应素试验滴度≥1∶16以及未进行治疗是发生不良妊娠结局的危险因素。更多还原

【Abstract】 Objective To explore the adverse pregnancy outcomes of pregnant syphilis and the influencing factors. Methods The clinical data of 91 pregnant syphilis patients was collected from a hospital from January 1st to July 31 st in 2015,the general demographic characteristics,obstetric characteristics and clinical characteristics were analyzed by univariate analysis and multivariate regression analysis.Results Univariate analysis showed that age and RPR serum titer of mothers of pregnant syphilis patients,receiving anti-syphilis treatment or not were correlated with adverse pregnancy outcomes. Multivariate analysis showed that RPR serum titer of mothers of pregnant syphilis patients( OR = 4. 388,P = 0. 017) and receiving anti-syphilis treatment or not( OR = 0. 064,P = 0. 001) were correlated with adverse pregnancy outcomes. Conclusion RPR serum titer of mothers of pregnant syphilis patients≥1 ∶ 16 and not receiving anti-syphilis treatment are the risk factors of adverse pregnancy outcomes.更多还原