【摘要】 目的探讨椎-基底动脉扩张延长症(VBD)患者的头磁共振FLAIR序列血管高信号征(FVH)与后循环血流、管径、动脉弹性的相关研究。方法收集2014年10月~2016年12月在辽宁省金秋医院住院,年龄≥65岁,经MRI和MRA检查确诊VBD患者46例,依据临床表现和磁共振弥散成像的检查结果诊断为后循环脑梗死,分为梗死组(27例),无梗死组(19例)。对两组患者的MRI图像基底动脉FVH等级与动脉直径、血管形态、经颅彩色多普勒血流速度及动脉弹性进行统计分析。结果 FVH在老年VBD患者的发生率为60.9%。VBD患者梗死组S型基底动脉较无梗死组多,两组存在统计学差异(χ~2=4.207,P=0.043)。基底动脉FVH征与血流平均速度、动脉搏动指数存在正相关(r分别为0.431、0.469,均P<0.05),中重度的FVH征(FVH≥2级)与基底动脉直径(r=0.506,P<0.05)弱相关。影像学上基底动脉FVH达到2级以上的梗死组较无梗死组在动脉管径更大、平均血流速度更慢,差异存在统计学意义(t=2.330,P=0.035;t=2.245,P=0.041)。结论 FVH征在VBD患者中出现率高。FVH征达到2级以上的VBD患者,预示基底动脉平均动脉血流速度(MFV≤20 m/s)减慢、动脉直径增大,提示发生后循环脑卒中的风险增大。更多还原

【Abstract】 Objective To investigate the study of the fluid attenuated inversion recovery vascular hyperintensity(FVH) and posterior circulation blood flow,vessel radius and arterial elasticity in patients with vertebrobasilar dolichoectasia(VBD). Methods We identified 46 patients with VBD,the age of 65 or higher,diagnosed by MRI and TOF MRA examination,collected in Jinqiu hospital of Liaoning province from October 2014 to December 2016. On the basis of clinical symptoms,magnetic resonance imaging to diagnose the existence of posterior circulation stroke,the patients divided into infarction group(27 cases) and non-infarction group(19 cases). The FVH grades of MR images with basilar arterial diameter,vascular morphology,the blood flow velocity and the arterial elasticity of the cranial color doppler,and the data of two groups were statistically analyzed. Results FVH demonstrated in 60. 9% of the patients with VBD in older. The S-type basilar artery of VBD patients in infarction group was more than the non-infarction group,and there were statistical differences(χ~2= 4. 207,P = 0. 043). The mean flow velocity,pulsatility index of basilar artery had positive correlation with FVH(r were 0. 431,0. 469,P < 0. 05),and basilar artery diameter had low correlation with higher FVH grade(2 and 3)(r =0. 506,P < 0. 05). A higher FVH grade in infarction group had larger diameter and lower mean flow velocity in comparison to non-infarction group,and the statistical differences(t = 2. 330,P = 0. 035; t = 2. 245,P = 0. 041). Conclusion FVH was a high ratio in patients with VBD. FVH achieved more than grade 2 indicated that the mean flow velocity of basilar artery(MFV 20 m/s or less) slow down,artery diameter increases. That prompted the occurrence of increased risk of postcirculation stroke.更多还原