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继发肺部感染对耐多药结核病患者转归的影响

Effect of secondary pulmonary infection on outcome of patients with multidrug-resistant tuberculosis

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【作者】 谭守勇梁卓智黎燕琼

【Author】 TAN Shou-yong;LIANG Zhuo-zhi;LI Yan-qiong;State Key Laboratory of Respiratory Diseases,Department of Pulmonary Tuberculosis,Guangzhou Chest Hospital;

【机构】 广州市胸科医院结核内科呼吸疾病国家重点实验室中山大学公共卫生学院

【摘要】 继发肺部感染(简称“肺部感染”)是造成和促进结核病患者死亡的重要因素。耐药结核病患者病程长、肺部病变广泛,是构成呼吸道继发感染的基础;同时患者长期住院、使用广谱抗生素、进行侵袭性操作易发生医院内下呼吸道感染。继发肺部感染将加重耐药肺结核患者肺组织损伤,加重耐药肺结核耐药程度,加重患者营养不良,从而降低患者对治疗的依从性。因此,对耐药肺结核患者要加强预防继发肺部感染的管理。

【Abstract】 Secondary pulmonary infection is the important factors to cause and promote tuberculosis(TB)patients death.The patients with drug-resistant TB have a long course and a wide range of lung lesions,which is the basis for the formation of secondary infection of respiratory tract Meanwhile,the patients with long-term hospitalization,the use of broad-spectrum antibiotics,invasive operation prone to nosocomial lower respiratory tract infection.Secondary pulmonary infection can aggravate lung tissue injury of patients with drug-resistant TB;increase the degree of drug-resistant TB and make the patients malnutrition heavier.All of this will reduce the patients compliance.Therefore,secondary pulmonary infection of patients with drug-resistant pulmonary TB should be prevent and manage strengthenly.

【基金】 广州市科技计划课题(155700012);广州市医药卫生科技重大项目(20151A031002)
  • 【文献出处】 中国防痨杂志 ,Chinese Journal of Antituberculosis , 编辑部邮箱 ,2017年05期
  • 【分类号】R52;R563.1
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