【摘要】 患者女,36岁。躯干、四肢皮肤浅色扁平丘疹20年。皮损发展缓慢,无明显症状。皮肤科情况:躯干、四肢皮肤出现大小不一的浅色扁平丘疹,其走向与皮纹方向一致,并伴有双上臂后侧出现以毛囊为中心的针帽大丘疹。部分皮疹融合成斑块。扁平皮疹处组织病理检查:表皮萎缩变薄;真皮胶原纤维变细,排列疏松。阿新兰染色:真皮未见明显黏蛋白沉积。弹力纤维染色:真皮中部可见弹力纤维明显减少或消失。诊断:真皮中层弹性组织溶解症。更多还原

【Abstract】 A 36-year-old woman presented with a 20-year history of light flat papules on the trunk and limbs. The lesions developed slowly and were asymptomatic. Skin examination revealed multiple irregularly sized light flat papules on the trunk and limbs along Langer’s lines,multiple pin cap-sized perifollicular papules on the posterior upper arm. Part of papules merged into plaques. Pathological examination of biopsy showed epidermal atrophy and thinning,and thinned collagen fibers arranged loosely in the dermis. Alcian blue staining revealed no mucoprotein in the dermis. Verhoeff-van Giesen’s Staining showed almost complete absence of elastic fibers in the mid dermis. Based on the above findings,the diagnosis was made as mid-dermal elastolysis.更多还原