【摘要】 抗栓治疗是急性冠脉综合征治疗的基础,可显著改善急性冠状动脉综合征患者的预后。但由于个体差异,部分患者在抗栓治疗后仍发生血栓或者出血事件,因此,进行血小板功能检测是必要的。本文一方面,通过对血栓弹力图工作原理及主要参数的描述,分析其在抗栓治疗中的应用,指出其优势与不足;另一方面,通过对阿司匹林抵抗、氯吡格雷抵抗的介绍,讲述基因检测在抗栓治疗中的应用现状。通过对上述两种方法在急性冠脉综合征抗栓治疗中应用的简述,为检测血小板聚集功能方法进一步发展提供依据。更多还原

【Abstract】 The treatment of acute coronary syndrome is based on antithrombotic therapy, which can significantly improve the prognosis of patients with acute coronary syndrome. But due to individual differences, some patients still develop into thrombosis or bleeding events after antithrombotic therapy. Therefore, it is necessary to tests platelet function. In this paper, on the one hand, according to the description of working principle and main parameters about thrombelastography, it analyzes its application in antithrombotic therapy, and points out its advantages and disadvantages. On the other hand, through to the introduction of the aspirin resistance and clopidogrel resistance, it tells about genetic testing on the application status of antithrombotic therapy. Through the description of the above two methods used in antithrombotic treatment of acute coronary syndrome, it provides the basis for the further development of platelet aggregation function of testing methods.更多还原