【摘要】 动脉粥样硬化(As)是一种与多种危险因素相关的复杂疾病。As形成的病理生理及发生和发展机制一直是心血管病研究领域的重点。而人类三大死亡原因之首则是急性心血管事件,约70%的急性心血管事件由As易损斑块的破裂及继发性血栓所致,故治疗As是防治人类心脑血管疾病的重要途径。As的治疗多从对抗其疾病的危险因素着手,目前临床上广泛应用的As治疗方法主要有血管重建术,包括经皮冠状动脉介入治疗,药物治疗主要为调节血脂、抗炎、抗氧化剂、抗血小板、降压及其他新兴药物。更多还原

【Abstract】 Atherosclerosis(As) is a complex disease with several risk factors.The pathophysiology of As and the mechanism of its occurrence and development have been the focus in the field of cardiovascular disease.Acute cardiovascular events are the first of the three leading causes of death in humans,about 70% of which are caused by the rupture of As vulnerable plaques and secondary thrombosis.Treatment of As is an important way to prevent cardiovascular and cerebrovascular diseases.The treatment of As is usually started with fighting against the risks of the disease,and the currently widely used treatment is mainly revascularization,including percutaneous coronary intervention,and drug treatment containing blood lipid adjusting,anti-inflammatory,antioxidant,anti-platelet,antihypertensive drugs and other emerging drugs.更多还原