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新生儿完全性肺静脉异位引流的外科治疗及效果分析

Risk Factors of Total Anomalous Pulmonary Venous Connection Operation in Neonates

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【作者】 张金涛李群

【Author】 Zhang Jintao;Li Qun;Cardiac center of The Third Affiliated Hospital of Zhengzhou University;

【机构】 郑州大学第三附属医院心脏中心

【摘要】 目的评价完全性肺静脉移位引流患儿在新生儿期实施手术的效果,分析手术的危险因素。方法收集笔者医院自2010年6月~2016年6月实施肺静脉移位引流纠治手术的新生儿21例,其中男性15例(71%),女性6例(29%),年龄中位数为20天,体重中位数为3.5kg,其中心上型10例,心内型6例,心下型4例,混合型1例;用Logistic回归方法对可能导致手术死亡的因素进行分析。结果住院死亡4例(19%),心上型1例,心内型1例,心下型2例;2例死于低心排,2例死于肺部感染;Logistic回归分析发现,术前肺部感染、解剖分型、主动脉阻断时间、体重分级为影响手术后治疗效果的危险因素。结论完全性肺静脉移位引流患儿在新生儿期实施手术治疗,可以取得比较满意的效果,术前肺部感染、解剖分型、主动脉阻断时间、体重分级是影响手术效果的危险因素。

【Abstract】 Objective To summarize the experience of surgical of complete pulmonary venous connection in neonates,and analyze the risk factors. Methods Between June 2010 to June 2016,21 consecutive neonates under went surgical correction of total anomalous pulmonary venous connection. There were 15 males and 6 females at mean age 20 d,and the mean weight was 3. 5kg. There were 10 patients with supracardiac,of which 6 patients with intracardiac,4 patients with infracardiac,and 1 patients with mixed. Clinical variables possibly associated with death were examined using Logistic regression analysis. Results There were 4 operative deaths( 19%),2 patients with supracardiac,1 patient with intracardiac,1 patient with infracardiac. 2 were died of low cardiac output syndrome,and 2 died of pneumonia. Logistic regression analysis showed that preoperative pulmonary infection,anatomic classification,aortic clamping time,weight were risk factors of operation. Conclusion Total anomalous pulmonary venous connection operation in neonates can obtain satisfactory results. Preoperative pulmonary infection,anatomic classification,aortic clamping time,weight are risk factors for operation.

【基金】 河南省高等学校重点科研基金资助项目(14B320029)
  • 【文献出处】 医学研究杂志 ,Journal of Medical Research , 编辑部邮箱 ,2017年08期
  • 【分类号】R722.1
  • 【被引频次】1
  • 【下载频次】73
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