【摘要】 目的探讨ICU老年患者发生呼吸机相关性肺炎(ventilator associated pneumonia,VAP)的危险因素。方法回顾性分析2014年1月至2016年12月于本院ICU住院并采取机械通气治疗的112例老年患者的临床资料,分析ICU老年患者发生VAP的危险因素。结果 112例老年患者中共发生VAP 28例(25.00%)。多因素Logistic回归分析显示:急性生理功能与慢性健康状况评分系统Ⅱ评分≥15分、气管插管/切开、ICU住院天数≥15天、机械通气时间≥7天、长期应用质子泵抑制剂、血清白蛋白水平<35 g/L、氧合指数<400 mm Hg均为ICU老年患者发生VAP的独立危险因素(P<0.05)。结论 ICU老年患者发生VAP的危险因素较多,临床上应结合相关危险因素,在保证治疗效果的基础上,采取有效的预防措施,减少VAP的发生。更多还原

【Abstract】 Objective To investigate the risk factors of ventilator associated pneumonia(VAP) in elderly patients of ICU. Method Retrospectively analyzed the clinical data of 112 elderly patients hospitalized in ICU in our hospital from January 2014 to December 2016 with mechanical ventilation. Analyzed the risk factors of VAP in elderly patients of ICU. Result 112 cases of elderly patients, VAP occurred in 28 cases(25.00%). Multivariate Logistic regression analysis showed that: acute physiology and chronic health evaluation Ⅱ score ≥ 15 points, tracheal intubation/incision, ICU length of stay ≥ 15 days, the time of mechanical ventilation ≥7 days, long-term use of proton pump inhibitors, serum albumin level < 35 g/L, the oxygenation index < 400 mm Hg were the risk factors of VAP in elderly patients of ICU(P < 0.05). Conclusion There are many risk factors for VAP in ICU elderly patients. Based on the related risk factors, effective preventive measures should be taken to reduce the incidence of VAP.更多还原