【摘要】 目的探讨多层螺旋CT灌注成像(CTP)联合CT门静脉造影(CTPV)技术对肝硬化诊断及肝功能储备分级的价值。方法将200例肝硬化患者按Child-Pugh分级标准分为Child-Pugh A组(n=74)、Child-Pugh B组(n=58)和Child-Pugh C组(n=68),均行CTP及CTPV检查,记录肝动脉灌注量(HAP)、门静脉灌注量(PVP)、肝总灌注量(THP)及门静脉主干(MPV)、肝内门静脉左支(IHLPV)和右支(IHRPV)的直径。结果随着Child-Pugh分级的增加,HAP、PVP、THP逐渐减小,三组比较,差异有统计学意义(P<0.05),Child-Pugh分级与PVP、THP显著相关(P<0.05),而与HAP无关(P>0.05);随着Child-Pugh分级的增加,MPV、IHLPV、IHRPV直径逐渐增大,三组比较,差异有统计学意义(P<0.05)。结论 CTP与CTPV相结合可为肝硬化的诊断及肝功能储备分级提供更加全面的影像学信息。更多还原

【Abstract】 Objective To investigate the value of multi-slice spiral CTP combined with CTPV in the diagnosis of liver cirrhosis and liver function reserve score. Methods Two hundred patients who were preliminarily diagnosed as cirrhosis were divided into Child-Pugh A group(n=74), Child-Pugh B group(n=58) and Child-Pugh C group(n=68) according to the Child-Pugh classification standard. All the patients were underwent CTP and CTPV examinations. The hepatic artery perfusion(HAP), portal venous perfusion(PVP), total hepatic perfusion(THP) and the diameter of man portal vein(MPV), intrahepatic left portal vein(IHLPV) and right portal vein(IHRPV) were recorded. Results With the increase of Child-Pugh classification, the HAP, PVP and THP gradually decreased, and the differences between the three groups were statistically significant(P<0.05). The Child-Pugh classification was significantly related to PVP, THP(P<0.05), and was not related to HAP(P >0.05). With the increase of Child-Pugh classification, the diameters of MPV, IHLPV and IHRPV gradually increased, and the differences between the three groups were statistically significant( P<0.05). Conclusion CTPV combined with CTP can provide more comprehensive imaging information for the diagnosis of liver cirrhosis and the classification of hepatic function reserve.更多还原