In the presence of FeCl_3 reaction of alkenols with iodine resulted in intramolecular addition of hydroxyl to alkenol to produce a wide range of iodocyclic ethers in good to excellent yields under mild reaction conditions. The advantages of our procedure include a decreased amount of iodine as well as short reaction times. The broad scope, mild reaction conditions, and experimental ease of this transformation have made it a valuable alternative to current available methods for the preparation of iodocyclic ...
【更新日期】
2017-06-07
【分类号】
O621.3
【正文快照】
*Corresponding authors.E-mail:pengxiangjun99@126.com;lxliu@xmu.edu.cnReceived October 31,2016;revised December 23,2016;published online January 10,2016.四氢呋喃环和四氢吡喃环都是非常重要的环醚类结构,此类杂环结构广泛存在于天然海洋产物中,其化学结构和生物活?