【摘要】 目的研究腹腔镜手术与开腹手术治疗肝内外胆管结石对机体免疫功能的影响。方法选取我院2015年6月至2017年6月收治的150例肝内外胆管结石患者,按照治疗方法的不同分为腹腔镜组(n=100)和开腹术组(n=50)。开腹术组行开腹手术治疗,腹腔镜组行腹腔镜手术治疗。观察并比较两组患者的手术指标、机体免疫功能指标及肝功能指标。结果腹腔镜组患者的术中出血量、手术切口长度、术后肛门排气时间、下床活动时间以及住院时间均显著少于开腹术组患者(P<0.05)。治疗后,腹腔镜组患者的机体免疫功能指标以及肝功能指标均显著优于开腹术组,差异有统计学意义(P<0.05)。结论应用腹腔镜治疗肝胆管结石具有显著的临床效果,患者创伤小,术后恢复快,对机体免疫功能和肝功能的影响较小。更多还原

【Abstract】 Objective To study the impact of laparoscopic surgery and laparotomy on the immunological function of patients with intra-and-extra hepatic cholangiolithiasis.Methods 150 cases of patients with intra-and-extra hepatic cholangiolithiasis admitted to our hospital from June 2015 to June 2017 were selected and divided into laparoscopic group(n = 100,laparoscopic surgery) and laparotomy group(n = 50,laparotomy) according to the treatment methods.The surgical indicators,body immunological function indicators,and hepatic function indicators were observed and compared between the two groups.Results The intraoperative blood loss,surgical incision length,postoperative anal exhaust time,evacuation active time and length of hospital stay of the laparoscopic group were significantly lower than those of the laparotomy group(P <0.05).After treatment,the body immunological function indicators and hepatic function indicators of the laparoscopic group were significantly better than those of the laparotomy group(P <0.05).Conclusions Laparoscopic surgery for the treatment of patients with hepatic cholangiolithiasis has significant clinical efficacy and less impact on body immunological function and hepatic function,with small trauma and fast postoperative recovery.更多还原