【摘要】 目的探讨术后放化疗在淋巴结阳性胸段食管鳞癌患者中的应用价值。方法选取我院收治的120例淋巴结阳性胸段食管鳞癌患者,分为放疗组和化疗组各60例。结果放疗组的5年总生存率为56.67%,显著高于化疗组的38.33%(P<0.05)。两组患者淋巴结转移1~2枚的5年生存率均明显高于淋巴结转移≥3枚(P<0.05)。化疗组的粒细胞减少和消化道反应总发生率均明显高于放疗组(P<0.05)。两组患者的肺部反应发生率比较差异无统计学意义(P>0.05)。结论术后放化疗在淋巴结阳性胸段食管鳞癌患者中具有重要应用价值,值得临床推广。更多还原

【Abstract】 Objective To explore the application value of postoperative radiotherapy and chemotherapy for patients with node-positive thoracic esophageal squamous cell carcinoma. Methods 120 cases of patients with node-positive thoracic esophageal squamous cell carcinoma admitted to our hospital were selected and divided into radiotherapy group and chemotherapy group, with 60 cases in each group. Results The total 5-year survival rate of radiotherapy group was 56.67%, significantly higher than 38.33% of chemotherapy group(P <0.05). The 5-year survival rates of patients with 1 to 2 lymph node metastasis in two groups were significantly higher than those of patients with more than 3 lymph node metastasis(P <0.05). The total incidences of granulopenia and gastrointestinal reactions of chemotherapy group were significantly higher than those of radiotherapy group(P <0.05). No statistical difference was found in the incidence of pulmonary reactions between two groups(P >0.05). Conclusions Postoperative radiotherapy and chemotherapy in patients with node-positive thoracic esophageal squamous cell carcinoma have important application value, which are worthy of clinical promotion.更多还原