【摘要】 目的探究乳腺癌化疗后对肌松药维库溴铵的影响。方法将该院2014年3月至2016年1月收治的准备接受手术治疗的94例乳腺癌患者按入院顺序分为研究组和对照组,每组47例。研究组术前接受化疗,同时给予保肝、保肾治疗;对照组术前不接受化疗。两组患者其他治疗方法基本相同。结果研究组患者肌松药起效时间与对照组比较,差异无统计学意义(P>0.05),但临床时效及恢复指数均明显高于对照组,差异均有统计学意义(P<0.05)。结论乳腺癌术前化疗会延长维库溴铵的临床时效及恢复指数,应根据患者个体差异调整维库溴铵用量。更多还原

【Abstract】 Objective To investigate the impact of chemotherapy on muscle relaxant vecuronium in breast cancer.Methods Ninety-four patients with breast cancer undergoing the operation treatment in our hospital from March 2014 to January 2016 were divided into the study group and control group according to the admission order,47 cases in each group. The study group received chemotherapy before operation,meanwhile was given liver protection and renal protection therapy; the control group received no chemotherapy before operation. Other treatments in the two groups were basically same. Results The onset time of muscle relaxant had no statistical difference between the study group and control group(P>0.05),but the clinical aging and recovery index in the study group were significantly higher than those in the control group,the difference was statistically significant(P<0.05). Conclusion Preoperative chemotherapy of breast cancer could prolong the clinical aging and recovery index of vecuronium,and the dosage of vecuronium should be adjusted according to individual differences.更多还原