【摘要】 目的 探讨颤动数（FibN）预测心脏性猝死（SCD）一级预防植入植入型心脏复律降颤器（ICD）有效性的价值。方法 FibN的临床应用:使用心电图和超声心动图参数QRS、QTc和LVEDd(记为FibN_VT/VF=LVEDd·QRS·QTc^-1)。通过起搏器程控仪调取我院符合SCD一级预防并植入ICD患者的起搏器数据,根据是否发生诊断正确的心血管事件（室性心动过速或心室颤动）及适当的ICD治疗分成2组,对比分析指标在两组间的统计差异程度。结果 FibN_VT/VF预测SCD一级预防植入ICD有效性的ROC曲线下面积为0.733（95%CI 0.613⁰.853）,且当FibN_VT/VF≥14.995时,敏感度为80%,特异度为64.3%（95%CI0.613⁰.875）。结论 FibN_VT/VF预测SCD一级预防植入ICD的有效性有临床应用价值。更多还原

【Abstract】 Objective To explore the predictive value of the fibrillation number（FibN） in patients with an ICD for primary prevention of SCD. Methods For clinical application of FibN, we used electrocardiography and echocardiography data: QRS interval, QTc, and LVEDd(FibN_VT/VF=LVEDd·QRS·QTc^-1). The follow-up data was divided into two groups according to whether the correct cardiovascular events（ventricular tachycardia or ventricular fibrillation） and the appropriate ICD therapy. The difference of indicators and optimal combination between the two groups was analyzed. Results The area under the ROC curve of FibN_VT/VF was 0.733. And FibN_VT/VF≥14.995,the sensitivity and specificity were 80% and 64.3% respectively. Conclusion This study results showed there was clinical application value of FibN_VT/VF in patients with an ICD for primary prevention of SCD.更多还原