【摘要】 目的探讨缺血性脑血管疾病(ICD)患者超氧化物歧化酶(SOD)与血栓弹力图(TEG)及常规凝血指标的相关性。方法取自我院住院的缺血性脑血管病(ICD)患者100例,其中脑梗塞45例,腔隙性脑梗塞23例,脑供血不足32例。对照组采用健康体检者50名。分别进行SOD,TEG和常规凝血指标的检测。结果 ICD组SOD值明显减少,TEG中R值和K值明显缩短。Angel角、MA值、CI值增高,Fbg、D-D值明显增高(P<0.05)。Pearson相关性分析显示:SOD与K值呈正相关(P<0.05),与Angel角、MA值、CI值、Fbg、D-D呈负相关(P<0.05)。结论 ICD患者SOD与TEG指标及Fbg和D-D有较强的相关性,SOD可以作为ICD诊断、治疗和预后判断中的筛选试验之一。更多还原

【Abstract】 Objective To investigate the relationship between superoxide dismutase( SOD) and thrombelastograph( TEG) and conventional coagulation detection in the patients with ischemic cerebrovascular diseases( ICD). Methods we were measured the SOD and TEG and conventional coagulation detection in the patients with ICD and the control group,the brain diseases group was made up of the male 100 cases that are45 patients with cerebral infarction,23 patients with cavity infarction and 32 patients with cerebral insufficiency. The control group used 50 physical examination. Results Compared with the healthy control group,the R value and K value were significantly shorted in the patients with ICD the angel,MA value,CI value and Fbg,D-D levels were significantly increased,the differences were statistically significant( P <0. 05). Pearson correlation analysis showed that SOD and K value were positively correlated and Angle,MA value,CI value,Fbg,D-D levels showed a negative correlation( P < 0. 05). Conclusion Between SOD and TEG; Fbg; D-D have strong correlation in the ICD,SOD can serve as practical value test for diagnosis,treatment and prognosis judge.更多还原