【摘要】 随着基因组学相关技术的快速发展,如何处理和利用海量的数据问题越来越重要,人类复杂疾病与基因、miRNA和lncRNA的关系也成为研究的热点之一.先阐述了随机游走算法的基本原理,随后分析了几类基于随机游走算法在基因、miRNA和lncRNA与疾病关系预测中的应用研究,最后对随机游走预测算在疾病相关关系预测方面的应用作了总结和展望.更多还原

【Abstract】 With the rapid development of genomic technology,how to deal with and use the massive biological data has become more and more important. The relationship between human complex diseases and genes has become one of the research hot spots. The basic principle of random walk algorithm is expounded. Then,the application of random walk algorithm based on random walk algorithm in genetic,mirRNAs,lncRNAs and disease relation prediction is analyzed. Finally the methods inferring the relationships with related diseases based on random walk algorithm are summarized and prospected.更多还原