【摘要】 目的探讨1996-2015年贵州省黔南州结直肠癌发病趋势,为科学地制定防治决策提供参考依据。方法采用贵州省黔南州1996-2015年癌症发病登记数据库资料,对结直肠癌作性别、年龄进行分析,计算指标包括粗发病率、中国人口标化率、世界人口标化率、35~65岁截缩率、0~75岁累积率、累积风险率、变化百分比及年均变化百分比等。结果 1996-2015年贵州省黔南州结直肠癌发病3 445例(男性1 670例,女性1 775例),平均粗发病率为18.59/10万(男性18.93/10万,女性18.25/10万)。结直肠癌病例数占贵州省黔南州全部癌症发病数的6.57%,居贵州省黔南州癌症发病的第4位。中国人口标化发病率6.59/10万,世界人口标化发病率10.54/10万,35~65岁截缩发病率为15.21/10万,0~75岁累积发病率为1.26%,结直肠癌发病的累积风险率为1.25%。20年中粗发病率、中国人口标化发病率、世界人口标化发病率的变化百分比分别为381.64%、68.47%和90.37%,年均变化百分比分别为4.25%、1.39%、1.59%。各时期结直肠癌发病率显示,40~44岁以上各年龄段发病率有明显上升趋势,≥85岁以后有所回落。男性和女性各年龄段结直肠癌发病率上升趋势基本一致,但男性上升幅度高于女性。结论贵州省黔南州20年来结直肠癌发病率有明显上升趋势,应引起高度重视。更多还原

【Abstract】 Objective To investigate the incidence trend of colorectal cancer from 1996 to 2015 in Qiannan area of Guizhou province,and to provide the basis for making control measures and strategies for prevention. Methods The cancer registration data of 1996-2015 were collected and analyzed for the incidence of colorectal cancer by gender and age. Crude incidence,age-standardized incidence by Chinese standard population( ASR China) and by world standard population( ASR world),truncated rate( 35 ~ 65 age years old),cumulative rate( 0 ~ 75 age years old),cumulative risk,percentage change( PC),and annual percentage change( APC) were calculated. Results The new colorectal cancer cases were 3445( male 1670,female1775),accounted for6. 57% of the total cancer incidence,ranked 4th. The crude incidence,ASR China and ASR world were18. 59/105( male 18. 93/105,female 18. 25/105),6. 59/105 and 10. 54/105,respectively. Truncated rate( 35 ~ 65 age years old),cumulative rate( 0 ~ 75 age years old) and cumulative risk were 15. 21/105,1. 26% and1. 25%,respectively. During the twenty years period,the PCs of crude incidence,ASR China and ASR world were + 381. 64%,+ 68. 47% and + 90. 37%,and the APCs,4. 25%,1. 39% and 1. 59%,respectively. Age-specific incidence by a period of colorectal cancer remarkably increased with age in people aged 40 ~ 44 years,age-specific incidence by a period of colorectal cancer remarkably decreased with age in people after aged 85 over years. Men and women all ages colorectal cancer incidence rates rise. But men rise than women. Conclusion The incidence of colorectal cancer remarkably increased in Qiannan area of Guizhou province during 1996-2015. More attention should be paid to the incidence trend of colorectal cancer.更多还原