【摘要】 目的探讨老年非ST段抬高型急性冠状动脉综合征(NSTE-ACS)患者入院时心电图QRS波群宽度(QRSw)与主要心脏不良事件(MACE)的关系。方法将137例老年NSTE-ACS患者按照入院时心电图QRSw分为QRSw≤100ms组和QRSw>100ms组。同时,按照患者住院期间是否发生MACE分为MACE组和非MACE组,并利用Logistic回归方程分析QRSw与MACE发生的关系。结果 QRSw≤100ms组95例,QRSw>100ms组42例,QRSw>100ms组血清c Tn I、CK-MB、hs-CRP、BNP水平及MACE发生率均高于QRSw≤100ms组,LVEF低于QRSw≤100ms组,差异均有统计学意义(均P<0.05)。MACE组31例,非MACE组106例。MACE组QRSw大于非MACE组,血清c Tn I、CK-MB、hs-CRP、BNP水平高于非MACE组,差异均有统计学意义(均P<0.05)。Logistic回归分析显示QRSw延长是老年NSTE-ACS患者住院期间发生MACE的危险因素(OR=1.213,95%CI:1.103~1.435,P<0.05)。结论 QRSw延长老年NSTE-ACS患者住院期间发生MACED的危险性增加。更多还原

【Abstract】 Objective To investigate the association of QRS wave width(QRSw) with in-hospital major adverse cardiac events(MACE) of elder patients with non-ST segment elevation acute coronary syndrome(NSTE-ACS). Methods137 elder patients with NSTE-ACS were divided into QRSw ≤100 ms group(group A, n=95)and QRSw>100 ms group(group B, n=42)based on ECG recorded at admission. Logistic regression analysis was performed for the relationship between QRSw and MACE. Results Serum c Tn I, CK-MB, hs-CRP and BNP levels were significantly higher and LVEF significantly lower in group B than in group A(all P<0.05). QRS was significantly wider, serum c Tn I, CK-MB, hs-CRP and BNP levels were significantly higher in 31 patients with MACE than in106 patients without MACE(all P <0.05). Logistic regression analysis showed that the increase of QRSwwas an independent risk factor of in-hospital MACE in elder patients with NSTE-ACS(OR = 1.213, 95%CI: 1.103~1.435, P<0.05). Conclusion The risk of in-hospital MACE increases in elder patients with NSTE-ACS and wide QRS.更多还原