【摘要】 目的探讨重症急性胰腺炎合并腹内高压、腹腔间隙综合征临床症状,比较各种不同方法早期干预IAH疗效,进一步提高SAP诊疗水平。方法选取44例急性胰腺炎患者作为研究对象,未合并IAH作为对照组,合并IAH作为研究组,同时给予特殊治疗,分为治疗组1和治疗组2,比较研究组和对照组临床指标,比较治疗组的两组患者治疗后腹内高压和生化指标。结果研究组患者腹腔内压、呼吸、心率、气道峰压、APACHEⅡ评分均高于对照组患者,动脉血氧饱和度、氧合指数、动脉血氧分压、每小时尿量均低于对照组患者,治疗组1患者治疗24、48、72 h较治疗组2患者显著降低,治疗后治疗组1的患者ALT显著低于治疗组2的患者,差异具有统计学意义(P<0.05)。结论重症急性胰腺炎合并腹内高压、腹腔间隙综合征较未合并IAH的患者临床症状显著,生命体征差,大黄口服或经鼻胃管注入联合芒硝外覆腹部治疗重症急性胰腺炎合并腹内高压、腹腔间隙综合征较一般常规治疗的患者降低腹内压更显著,且生化指标平稳,值得进一步在临床上推广。更多还原

【Abstract】 Objective To analyse the clinical indicators of severe acute pancreatitis with abdominal pressure, abdominal compartment syndrome symptoms. Compared the different methods of early intervention IAH effect, in order to improve the diagnosis and treatment of SAP. Methods Selected 44 cases of acute pancreatitis patients as research subjects. Unconsolidated IAH as a control group, the study group as a merger IAH,while giving special treatment, divided into treatment group 1 and group 2. To compare the clinical indicators of study group and the control group, and compared two groups of patients in the treatment group of IAH and biochemical indices after treatment. Results The study group patients with intra-abdominal pressure, respiration, heart rate, peak airway pressure, APACHEⅡ rates were higher in patients with arterial oxygen saturation,oxygenation index, blood pressure, urine output per hour were lower than the control group, the treatment group 1 patients 24 h, 48 h, 72 h compared with the treatment group 2 patients significantly decreased in patients with treatment group 1 ALT was significantly higher in patients treated group 2, the difference was statistically significant(P < 0.05). Conclusion The severe acute intra-abdominal pressure, abdominal compartment syndrome than those without significant clinical symptoms in patients with IAH merger poor vital signs, oral or nasogastric rhubarb mirabilite overcoat abdomen injection therapy with severe acute abdominal hypertension,abdominal compartment syndrome is more hemodialysis treatment reduces intra-abdominal pressure is more significant and stable biochemical indices, is worthy of further promotion in clinical practice.更多还原