【摘要】 背景:新型医用β钛合金Ti2448(Ti-24Nb-4Zr-7.9Sn)是迄今为止初始杨氏模量最低的钛合金,其初始杨氏模量约40 GPa,平均杨氏模量<20 GPa,抗拉强度约900 MPa,与人体组织的生物相容性和力学相容性优异。目的:探讨新型低弹性模量脊柱椎弓根螺钉内固定系统的生物力学性能,并与Ti6Al4V椎弓根螺钉进行比较。方法:取60个新鲜人尸体胸椎椎体标本,随机选择一侧椎弓根置入新型低弹性模量Ti2448椎弓根螺钉,另一侧椎弓根置入Ti6Al4V椎弓根螺钉,检测两组螺钉的最大弯曲载荷与最大载荷时位移、最大旋入力矩及最大轴向拔出力。结果与结论:两组螺钉的最大弯曲载荷、最大载荷时位移、最大旋入力矩、最大拔出力比较差异均无显著性意义。结果表明,新型低弹性模量Ti2448椎弓根螺钉内固定系统的最大弯曲强度、最大旋入力矩、最大拔出力与Ti6Al4V螺钉基本一致,可满足脊柱生物力学在内固定强度方面的需求。更多还原

【Abstract】 BACKGROUND: A new type of medical titanium alloy Ti2448(Ti-24Nb-4Zr-7.9Sn) is by far the lowest initial modulus of titanium alloy, with the initial modulus of about 40 GPa, the average Young’s modulus < 20 GPa, and tensile strength of about 900 MPa; human tissue biocompatibility and mechanical compatibility are excellent. OBJECTIVE: To investigate the biomechanical properties of a new low elastic modulus spinal pedicle screw fixation system and compare it with Ti6Al4 V pedicle screw. METHODS: Totally 60 fresh human cadaveric thoracic vertebrae were randomly selected: on one side, pedicle new low modulus Ti2448 pedicle screws, as the experimental group; on the other side, pedicle screw Ti6Al4 V, as control group. The maximum bending load and maximum load displacement, maximum torque and maximum axial pulling force of the two groups were detected.RESULTS AND CONCLUSION: There was no significant difference in the maximum bending load, maximum load displacement, maximum torque and maximum pulling force between the two groups. The results show that the maximum bending strength, the maximum torque and maximum pullout force in low elastic modulus of Ti2448 pedicle screw fixation system are consistent with the Ti6Al4 V screws, which can meet the needs of internal fixation on spinal biomechanics strength.更多还原