[Objective] We explored the role of mobile plasmids in transferring antimicrobial resistant genes in extended-spectrum beta-lactamases(ESBLs)-producing Escherichia coli from a wastewater treatment plant. [Methods] Based on the conjugation experiments of ESBL-producing E. coli collected from wastewater, the disk diffusion assay and polymerase chain reaction(PCR) were used to determine the transfer of antimicrobial resistance. [Results] A total of 50 ESBL-producing E. coli were collected from 80 water samples...