As a broad-spectrum antibacterial agent,berberine is widely applied in the field of Chinese traditional medicine,which is mainly used in treatment of intestinal bacterial infections in clinic. Intestinal mucosa immunity is the first line of defending against infection,and plays an important role in the establishment and maintenance of the mucosal homeostasis between the host and the environment. In recent years,the effect of Chinese traditional medicine in intestinal mucosa immunity has become the focus at ...