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三种不同治疗方法对带状疱疹后遗神经痛的临床疗效及安全分析

Clinical Effect and Safety Analysis of Three Different Treatment Methods for Postherpetic Neuralgia

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【作者】 于志坚

【Author】 YU Zhi-jian;Pain Department, Jiangxia District the First People’s Hospital of Wuhan;

【机构】 武汉市江夏区第一人民医院疼痛科

【摘要】 目的比较分析三种不同方案治疗带状疱疹后遗神经痛(PHN)的疗效及安全性。方法选择2015年3月至2017年3月我院就诊的132例PHN患者,按随机数字表法将其分为A、B、C 3组,每组44例。A组给予单纯西药治疗,B组给予单纯中药治疗,C组给予中西药结合治疗,比较3组临床疗效、治疗前、后疼痛视觉模拟评分(VAS)及不良反应等。结果 C组VAS评分明显低于A组和B组(P<0.05),而A组与B组比较差异无统计学意义(P>0.05);C组治疗总有效率(90.91%)明显高于A组(65.91%)和B组(70.45%)(P<0.05)。C组不良反应发生率(9.09%)明显低于A组(20.45%)和B组(18.18%)(P<0.05)。结论中西药结合治疗带状疱疹后遗神经痛疗效明确,不良反应少,安全可行。

【Abstract】 Objective to compare effect and safety of three different treatment schemes of postherpetic neuralgia(PHN). Methods choose 132 cases PHN patients treated in our hospital from March 2015 to March 2017, divide them into 3 groups randomly, group A, B and C, 44 cases in each. Group A was treated with western medicine only, group B with traditional Chinese medicine, and group C with combination of Chinese and Western medicine. Compared clinical effect, visual analogue scale(VAS) and adverse reactions before and after treatment between 3 groups. Results VAS scores of group C were significantly lower than group A and B,(P < 0.05), and there is no significant difference between group A and B(P > 0.05); total effective rate of group C(90.91%) was significantly higher than group A(65.91%) and B(70.45%)(P < 0.05). Adverse reactions incidence of group C(9.09%) was significantly lower than group A(20.45%) and B(18.18%),(P < 0.05). Conclusion combination of Chinese and western medicine is effective and safe in treatment of postherpetic neuralgia, with less adverse reactions.

  • 【文献出处】 世界最新医学信息文摘 ,World Latest Medicine Information , 编辑部邮箱 ,2017年92期
  • 【分类号】R752.12
  • 【被引频次】1
  • 【下载频次】84
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