【摘要】 目的研究辽宁阜新农村地区≥60岁老年人群不同年龄段血压与不良结局发生的相关性,探讨不同年龄段血压控制最适值。方法将纳入人群按60~69岁、≥70岁两个年龄段进行分层,采用Cox比例风险回归模型,在调整其他混杂危险因素后,探究不同年龄段血压与不良结局之间的关系。结果 60~69岁年龄段,相比参照组(收缩压120~129 mm Hg),收缩压<120 mm Hg或者≥140 mm Hg时,不良结局发生的风险性更高;≥70岁年龄段,相比参照组(收缩压130~139 mm Hg),收缩压<120 mm Hg或者≥150 mm Hg时,不良结局发生的风险性更高。60~69岁年龄段,相比参照组(舒张压80~89 mm Hg),舒张压<80 mm Hg或者≥90 mm Hg时,不良结局发生的风险险性更高;≥70岁年龄段,相比参照组(舒张压80~89 mm Hg),舒张压<80 mm Hg或者≥90 mm Hg时,不良结局发生的风险性更高。结论对于辽宁阜新农村地区≥60岁老年人群,60~69岁年龄段收缩压控制在120~139 mm Hg,舒张压控制在80~89 mm Hg,不良结局发生的风险性更低;≥70岁年龄段收缩压控制在120~149 mm Hg,舒张压控制在80~89 mm Hg,不良结局发生的风险性更低。更多还原

【Abstract】 Objective To explore the optimal blood pressure( BP) among different age groups in population aged ≥60 years.Methods Total 8 516 residents aged ≥60 years were selected from Fuxin rural area,including 4 897 aged 60-69 and 3 619 aged ≥70.After adjusting confounding factors,the relationships between BP and adverse outcomes were analyzed by Cox proportional hazards regression model.Results Compared with reference set of systolic blood pressure( SBP of 20-129 mm Hg),subjects aged 60 to 69 years with SBP < 120 mm Hg or SBP≥140 mm Hg had a higher risk for adverse outcomes; subjects aged ≥70 years with SBP < 120 mm Hg or SBP≥150 mm Hg had a higher risk for adverse outcomes compared with reference set( SBP of 130-139 mm Hg).For diastolic blood pressure( DBP),subjects both in 60 ~ 69 age group and ≥70 age group with DBP < 80 mm Hg or DBP≥90mm Hg had a higher risk for adverse outcomes compared with reference set( DBP of 80-90 mm Hg).Conclusion The study from Fuxin rural area indicates that if SBP could be controlled within 120-139 mm Hg,DBP could be controlled within 80-89 mm Hg,people in age group 60-69 years would have a lower risk of adverse cardiovascular outcomes; while for those in age group ≥70 years the SBP and DBP should be controlled to 120-149 mm Hg and 80 ~ 89 mm Hg,respectively.更多还原