目的探讨食管胃交界部癌(carcinoma of esophagogastric junction,CEJ)发生腹腔及胸腔纵隔淋巴结转移的危险因素,以指导是否清扫胸腔纵隔淋巴结。方法采用回顾性研究分析行食管胃交界部癌根治术的217例患者,分析术前胃镜及术后病理检查结果。结果淋巴结转移阳性数目是发生胸腔纵隔淋巴结转移独立的危险因素,且淋巴结转移数目每增加1个,纵隔淋巴结发生转移风险增加34.0%(OR=1.340,95%CI:1.090~1.648;P=0.006);脉管瘤栓(OR=5.83,95%CI:1.65~20.62,P=0.006)、浸润深度T(OR=2.35,95%CI:1.30~4.24,P=0.005)和上侵食管长度(OR=1.29,95%CI:1.02~1.63,P=0.033)是发生腹腔淋巴结转移的独立危险因素,而且上侵及食管每增加1 cm,发生腹腔淋巴结转移的风险增加29.0%。结论浸润深度越深、存在脉管瘤栓且上侵及食管越多的食管胃交界部癌患者发生腹腔淋巴结转移的风险越高。淋巴结转移数目越多,纵隔淋巴结发生转移的风险加大。
【英文摘要】
Objective To explore the risk factors of abdominal and thoracic mediastinal lymph node metastasis in carcinoma of esophagogastric junction( CEJ) and provide guidance for the necessity of mediastinal lymph node dissection.Methods Two-hundred-and-seventeen patients who have received CEJ radical resection were enrolled. The results of their pre-operative gastroscope test and post-operative pathological examination were analyzed. Results The number of metastatic lymph nodes was an independent risk factor for th...
【更新日期】
2017-06-21
【分类号】
R735
【正文快照】
食管胃交界部癌(carcinoma of esophagogastricjunction,CEJ)由于其独特的解剖学位置(位于食管的鳞状上皮及胃的柱状上皮的移型处),所以在其诊断和病理分期等诊疗方面一直备受争议。这个近90°的过渡处具有隐蔽性,早期病灶隐蔽,不易发现,极易漏诊;并且其具有阻塞食物通道的特性