【摘要】 目的:检测CaO/ZnO核-壳结构纳米球材料的抑菌性能。方法:采用液相沉淀法制备CaO/ZnO核-壳结构纳米球,测定该材料与丁香油酚调拌的材料钙离子释放和p H值,电子显微镜观察其形态及粒径,电感耦合等离子体(ICP)分析其离子组成;通过琼脂扩散法检测该材料对变形链球菌、粪肠球菌、大肠杆菌和金黄色葡萄球菌的抑制情况。结果:CaO/ZnO核-壳结构纳米材料的颗粒接近球形,粒径为80~90 nm,具有核-壳结构,由CaO和ZnO组成;在PBS中CaO/ZnO核-壳结构纳米球材料p H值和钙离子累积释放量随时间增加而递增,抑菌性优于iRoot SP和氧化锌-丁香油糊剂(P﹤0.01)。结论:CaO/ZnO核-壳结构纳米球材料具有优良的抑菌性。更多还原

【Abstract】 Objective: To study the antimicrobial properties of CaO/ZnO core-shell nanoparticles. Methods: The CaO/ZnO coreshell nanoparticles were prepared via precipitation method. The p H and calcium ion release from the samples which composed of eugenol and nanoparticles were examined respectively. The form of the particles was observed under electron microscope,the ions were analysed by inductively coupled plasma( ICP). The antibacterial activities against Streptococcus mutans,Enterococcus faecalis,Escherichia coli and Staphylococcus aureus were evaluated by agar diffusion test( ADT). Results: CaO/ZnO core-shell nanoparticles were spherical with core-shell structure and with the diameter of 80-90 nm. The calcium ion release and p H were gradually increasing from the nanoparticles in PBS. The antibacterial activity of CaO/ZnO core-shell nanoparticles-eugenol was significantly greater than that of iRoot SP and zinc oxide-eugenol sealer( P < 0. 01). Conclusion: CaO/ZnO core-shell nanoparticles possess antibacterial activity.更多还原