【摘要】 目的 分析Xp11.2易位/TFE3基因融合相关性肾细胞癌(Xp11.2 RCC)的CT表现,提高诊断的准确性。方法 回顾性分析12例经病理证实的Xp11.2 RCC的临床表现、影像学及病理学特征。结果 12例均为实性肿块,11例椭圆形或类圆形,1例形态不规则。CT平扫为等密度或稍高密度,密度多不均匀,11例肿瘤内部有囊变、坏死区,7例有点状或斑片状钙化,增强后呈中度或明显延迟强化。1例有腹膜后淋巴结转移,1例有肾门软组织肿块形成,1例有肾上腺转移,1例有腰大肌和L5椎体受侵。结论Xp11.2 RCC的CT表现有一定的特征性,当肿瘤在平扫上为等密度或稍高密度,伴有坏死或钙化,增强后中度或明显延迟强化,应考虑到此病的可能。更多还原

【Abstract】 Objective To analyze the CT features of renal carcinoma associated with Xp11,2 translocations/TFE3 gene fusions(Xp11,2 RCC),and to improve the diagnostic accuracy.Methods Clinical data,CT imaging and pathological features of 12 cases with pathology proved Xp11.2 RCC were analyzed retrospectively.Results All the 12 cases were solid masses.11 cases were oval or quasi-circular,1 case was irregular.Tumors were iso-density or hyperdensity on CT plain scan images.The density was heterogeneous,combined with necrosis in 11 cases and spotty or patchy calcification in 7 cases.After injection of contrast,moderate or obvious enhancement of tumors was found,1 case had retroperitoneal lymph node metastasis,1 case was found with mass formation in the renal hilus,1 case had adrenal metastasis.Another one was found with psoas major muscle and lumbar 5 invaded.Conclusion The Xp11.2 RCC has certain CT characteristics.This disease should be considered when a renal tumor is iso-density or hyperdensity on the CT plain scan images and has moderate or obvious enhancement,combined with necrosis or calcification.更多还原