Objective: To investigate the influence of down-regulating miR-582-3p effect on the proliferation,migration and apoptosis on gastric cancer SGC-7901 cells. Methods: Human gastric cancer SGC-7901,MKN28 cell and gastric epithelial cell EGS-1 were detectied by RT-PCR,miR-582-3p to detecteded the highest expression of miR-582-3p cells. Synthesis of miR-582-3p inhibitor transfection SGC-7901 cells,the experiment was divided into 3 groups: Blank control group RPMI 1640 + SGC-7901 cells. Negative control group RPM...
【更新日期】
2017-08-25
【分类号】
R735.2
【正文快照】
Modern Oncology 2017,25(17):2716-2720【作者单位】1陕西省人民医院普外二科,陕西西安7100682西安交通大学第一附属医院普外科,陕西西安710061周期出现明显阻滞,停滞在G2/M期(P<0.05),第48小时实验组细胞出现明显凋亡(P<0.05),Transwell实验表明下调miR-582-3p的表达能够抑制