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左乙拉西坦治疗小儿癫痫110例疗效及对患儿生活质量的影响

Study on the treatment effect of levetiracetam for 110 children with epilepsy and the effect on the quality of life

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【作者】 徐晓科王治静汪东赵斯钰张艳

【Author】 Xu Xiaoke;Wang Zhijing;Wang Dong;Department of Neurology,Xi’an children’s Hospital;

【机构】 西安市儿童医院神经内科西安市第四医院儿科

【摘要】 目的:探讨左乙拉西坦治疗小儿癫痫的有效性、安全性及对患儿生活质量的影响。方法:将220例小儿癫痫患者根据其治疗方式分为两组,观察组110例患者使用左乙拉西坦治疗,对照组110例患者使用丙戊酸钠治疗,观察并比较两组患者的治疗效果。结果:(1)观察组患者治疗有效率为95.45%,明显高于对照组的79.09%(P<0.05);(2)治疗前,两组患者认知功能评分无统计学差异(P>0.05),而治疗后,观察组上述指标值明显高于对照组(P<0.05)。结论:左乙拉西坦治疗小儿癫痫,提高患者认知功能,改善其生活质量,治疗安全有效。

【Abstract】 Objective:To study on the efficiency and safety of levetiracetam in the treatment process of epilepsy for children and the effect on the quality of life.Methods:The 220 children with epilepsy were divided into observation group and control group according to different methods.The patients were treated with levetiracetam in the observation group(n =110),while the patients were treated with sodium valproate in the control group(n =110).The treatment effects were observed and compared.Results:(1)The effective rate in the observation group was 95.45%,which was significantly higher than 79.09%in the control group patients(P<0.05).(2)There was no significant difference between these two groups about the score of cognitive function before treatment(P>0.05).After treatment,the values of index in the observation group were higher significantly(P<0.05).Conclusion:Levetiracetam is used to children with epilepsy,and it strengths the cognitive function of patients with improved their quality of life.The treatment is safe and effective.

  • 【文献出处】 陕西医学杂志 ,Shaanxi Medical Journal , 编辑部邮箱 ,2017年09期
  • 【分类号】R742.1
  • 【被引频次】28
  • 【下载频次】92
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