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可触摸低温等离子体对硅胶手的消毒灭菌实验研究

Experimental study on silicone hand disinfection by a touchable non-thermal plasma

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【作者】 郑超寇艳芹刘振姜红强黄逸凡闫克平

【Author】 ZHENG Chao;KOU Yanqin;LIU Zhen;JIANG Hongqiang;HUANG Yifan;YAN Keping;Zhejiang Center for Medical Device Adverse Event Monitoring and Safety Research;College of Chemical and Biological Engineering, Zhejiang University;

【机构】 浙江省医疗器械不良事件监测和安全研究中心浙江大学化学工程与生物工程学院

【摘要】 本文采用自主研制的可触摸式低温等离子体系统,研究了等离子体对硅胶手表面的消毒灭菌效果,以模拟和评估对人手的处理。等离子体处理硅胶手表面的金黄色葡萄球菌、大肠杆菌、白色葡萄球菌和铜绿假单胞菌时,并无显著差异。等离子体的消毒灭菌效率随时间的延长而提高,随细菌初始密度的增高而降低。细菌初始数量为1.0×10~6~1.0×10~7 CFU时,灭菌过程主要发生在前5 s,灭菌率在99%以上。本研究为研制可用于人手的新型等离子体设备奠定了基础。

【Abstract】 In this study, silicone hand was disinfected by homemade touchable non-thermal plasma to simulate and evaluate its feasibility of application on human hand. Experimental results showed that there was no significant difference when Escherichia coli(E. coli), Staphylococcus aureus(S. au), Staphylococcus albus(S. al), and Pseudomonas aeruginosa(P. ae) were loaded on the silicone hand surface and treated with plasma. The efficiency of plasma disinfection was higher when the treatment time was prolonged or initial bacterial density was lower. When initial bacterial number was 1.0×106–1.0×107 CFU, the plasma disinfection process mainly occured in the first 5 s and more than 99% of bacteria could be disinfected. This study can provide guidelines for the development of a new plasma device for human hand disinfection.

【基金】 浙江省科技计划项目资助(2015F10011,2014C33022)
  • 【文献出处】 生物医学工程学杂志 ,Journal of Biomedical Engineering , 编辑部邮箱 ,2017年02期
  • 【分类号】R187
  • 【被引频次】2
  • 【下载频次】191
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