【摘要】 目的:探讨一种声弹性成像定量分析方法用于评价深静脉血栓(DVT)患者血栓进展的情况。方法:经处理得12条大隐静脉标本,采用声弹性成像技术分别在1d、3d、6d、9d采集静脉标本中血凝块声弹性图像;应用等硬度区域面积测量技术(AMEHR)进行处理,计算血凝块区域在静脉标本中所占的比例,并进行数据分析。结果:经由AMEHR技术分析,在1d、3d、6d、9d静脉标本中,血凝块区所占比例分别为46.72%±12.16%,71.93%±7.24%,82.17%±5.17%,91.92%±3.69%。随着血栓时间的增加,血凝块区域所占比例逐渐增加,且差异有统计学意义(P<0.05);随着时间的进展,血凝块增长的速率逐渐降低(1-3d:25.21%,3-6d:10.24%,6-9d:9.75%)。结论:AMEHR技术对血栓形成时间的评估上有一定的应用价值,有望为评估血栓形成时间提供参考。更多还原

【Abstract】 Objective: To investigate a novel elastography quantification approach for the evaluation of thrombus progression in deep vein thrombosis(DVT) patients. Methods: Twelve saphenous vein samples were harvested through operating and reorganizing. The elastography images of blood clots were obtained by elastography technology in 1 d, 3 d, 6 d and 9 d, respectively. AMEHR(Area Measurement of Equal Hardness Region) program was applied to analyze all images. The proportion of blood clots in images was calculated and analyzed. Results: Through the analysis of AMEHR, the proportion of blood clots were 46.72%±12.16%, 71.93%±7.24%, 82.17%±5.17% and 91.92%±3.69% in 1 d, 3 d, 6 d and 9 d, respectively. The proportion of blood clots increased during different time(P<0.05). As the time went by, the increasing rate of blood clots was gradually decreased, it was 25.21%, 10.24% and 9.75%, respectively.Conclusions: AMEHR technology was proved to be valuable to evaluate the thrombus progression, which was hoped to provide references for the determination of thrombus stage.更多还原