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口服普萘洛尔治疗婴幼儿血管瘤疗效的临床观察

Clinical Effect of Oral Propranolol in the Treatment of Infantile Hemangioma

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【作者】 彭立红唐世杰郑映玲谢思田

【Author】 PENG Li-hong;TANG Shi-jie;ZHENG Ying-ling;XIE Si-tian;Department of Bumand Plastic Surgery,the Second Affiliated Hospital, Shantou University Medical College;

【机构】 汕头大学医学院第二附属医院整形烧伤外科暨唇腭裂治疗中心

【摘要】 目的:评估口服普萘洛尔治疗婴幼儿血管瘤的临床疗效和安全性。方法:对确诊为血管瘤的18例婴幼儿采用口服普萘洛尔(2.0 mg·kg-1·d-1,分2次口服)治疗;每4周复诊1次,拍照观察血管瘤的大小、质地、颜色变化;根据Achauer标准进行疗效评价。结果:口服普萘洛尔69个月时,疗效Ⅰ级(差)0例,Ⅱ级(中)1例,Ⅲ级(好)8例,Ⅳ级(优)9例:出现腹泻1例,余无不良反应。结论:口服普萘洛尔治疗婴幼儿血管瘤疗效好,安全性高,值得在临床应用。

【Abstract】 Objective: To investigate the efficacy of propranolol in the treatment of infantile hemangiomas(IHs). Eighteen cases of IHs were treated with oralpropranolol in the hospital. Changes in size, texture, color of the hemangiomas were observed at 4 weeks interval.The results were evaluated by using Achauer’ s system. Results: The mediation duration was 6-9 months. The overall response was grade Ⅱ in 1 patients, grade Ⅲ in 8 patients and grade Ⅳ in 9 patients. 1 patients was observed mild diarrhea. Conclusions:The study indicates that oral propranolol is effective and safe in treating IHs.

  • 【文献出处】 汕头大学医学院学报 ,Journal of Shantou University Medical College , 编辑部邮箱 ,2017年04期
  • 【分类号】R732.2
  • 【被引频次】1
  • 【下载频次】86
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