【摘要】 目的了解青岛市妇女儿童医院小儿毛细支管炎的病原体感染情况及构成特点。方法应用9项呼吸道病原联合试剂,对424例确诊为毛细支管炎的病儿病原体进行检测。结果 424例病儿中共检出病原体阳性病儿263例,男女病儿的病原体检出率差异无显著性(P>0.05)。毛细支气管炎以冬春季高发,主要感染病原体是呼吸道合胞病毒;夏秋季主要感染病原体为支原体。肺炎支原体感染率有逐年增高的趋势。9种联合检测病原体中,单一检出第一位的病原体为呼吸道合胞病毒,其次分别为肺炎支原体和副流感病毒;混合感染以两重病原混合感染多见。结论呼吸道合胞病毒是小儿毛细支气管炎的主要病原体,支原体感染有逐年上升的趋势,混合感染的增多应引起足够重视。更多还原

【Abstract】 Objective To investigate pathogen infection and composition features in children with bronchiolitis in Qingdao Women and Children’s Hospital,China. Methods Pathogen samples from 424 children definitely diagnosed with bronchiolitis were examined using a combined reagent for 9 respiratory pathogens. Results A total of 263 pathogen-positive cases were screened out from the 424 children.There was no significant difference in pathogen detection rate between male and female children with bronchiolitis(P>0.05).Bronchiolitis was predominant in winter and spring,and the main pathogen was respiratory syncytial virus(RSV).Mycoplasma was the major pathogen in summer and autumn.Moreover,the mycoplasma infection rate gradually increased year by year.Among the 9 pathogens,RSV was most common in single infection,followed by mycoplasma and parainfluenza virus.Dual-pathogen infection was most common among the cases of mixed infection. Conclusion RSV is the primary pathogen of pediatric bronchiolitis,and mycoplasma infection has an increasing trend year by year.Additionally,increasing mixed infection should be paid more attention to.更多还原