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CO2激光与等离子两种方法治疗喉乳头状瘤的疗效对比

Comparative study on Therapeutic Effectiveness of CO2 Laser and Low-temperature Plasma on Laryngeal Papilloma

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【作者】 魏锐文范敏崔榕蒋锐明蒋亚林

【Author】 Wei Ruiwen;Fan Min;Cui Rong;Chengdu Seventh People’s Hospital;Chengdu Tenth People’s Hospital;

【机构】 成都市第七人民医院成都市第十人民医院

【摘要】 目的评估两种方法治疗喉乳头状瘤的疗效及安全性。方法随机将63喉乳头状瘤患者分为两组,A组采用显微镜下CO2激光切除,B组采用7070号低温等离子射频刀头切除。比较两组患者的声带粘连、术后复发及恶变情况。结果 CO2激光治疗组较等离子治疗组复发率低,差异有统计学意义(P=0.027);对单发病灶患者,CO2激光治疗组较等离子治疗组复发率低,差异有统计学意义(P=0.040);对多发病灶患者,CO2激光治疗组与等离子治疗组复发率比较,差异无统计学意义(P=0.395);CO2激光治疗组较等离子治疗组声带粘连发生率低,差异有统计学意义(P=0.027)。复发主要发生在术后12个月以内,尤其是术后6个月。结论 CO2激光治疗喉乳头状瘤安全、有效,并发症少。

【Abstract】 Objective To evaluate the efficacy and safety of CO2 laser and low-temperature plasma. Methods 63 patients with laryngeal papilloma were randomly divided into two groups.A group was treated with CO2 laser under microscope while B group was treated with CoblatorT M Reflex#7070.Vocal cord adhesion,postoperative recurrence and malignant transformation of two groups were compared.Results CO2 laser group had a lower rate of recurrence than low-temperature plasma group( P = 0. 027).For patients with single lesion,CO2 laser group had a lower rate of recurrence than low-temperature plasma group( P = 0. 040).For patients with multiply lesions,there were no statistical differences between two groups( P = 0. 395).Compared with low-temperature plasma group,the incidence of vocal cord adhesion in CO2 laser group was lower( P = 0. 027). The recurrence mainly happened within 12 months after operation,especially within 6 months after operation.Conclusion CO2 laser is safe and efficient and causes few complications in the treatment of laryngeal papilloma.

  • 【文献出处】 四川医学 ,Sichuan Medical Journal , 编辑部邮箱 ,2017年07期
  • 【分类号】R739.65
  • 【被引频次】10
  • 【下载频次】134
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