Objective:To study the antidepressant effect of helicid on mice behavioral despair models.Methods:Sixty Kunming male mice were randomly divided into six groups(n=10).The helicid groups of four doses(20,30,40,50 mg·kg~(-1));positive control group(Imipramine hydrochloride,IMI,45mg·kg~(-1));the control group(distilled water).The drug was given by intragastric administration.By observing for six minutes,the accumulative immobility time of the final five minutes of dose group and control group was recorded in th...
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