化脓性关节炎血清降钙素原及血沉与C-反应蛋白联合检测诊断的临床价值

【摘要】 目的:探讨血清降钙素原(PCT)、血沉(ESR)及C-反应蛋白(CRP)联合检测诊断化脓性关节炎的临床价值。方法:选取2014年1月~2016年1月期间在我院收治的56急性关节炎患者,其中化脓性关节炎24例,作为观察组;非化脓性关节炎32例,作为对照组,比较两组患者的PCT、ESR、CRP水平及各检测指标的灵敏度、特异性。结果:观察组患者的PCT、ESR、CRP水平明显高于对照组,观察组PCT、ESR、CRP的阳性率均明显高于对照组,P<0.05,差异具有统计学意义。PCT、ESR及CRP联合检测的灵敏度明显高于任何单一指标检测的灵敏度,P<0.05,差异具有统计学意义。三者联合检测的特异性与PCT单独检测的特异性无明显差差异,P>0.05,差异无统计学意义。结论:PCT、ESR、CRP联合检测可提高化脓性关节炎诊断的准确度、灵敏度及特异性,在化脓性关节炎诊断方面具有较高的临床价值。更多还原

【Abstract】 objective: to investigate the serum calcitonin(PCT), blood sedimentation(ESR) and C-reactive protein(CRP) to detect the clinical value in the diagnosis of septic arthritis. Methods: selected from January 2014 to January 2014 in our hospital during the period of 56 patients with acute arthritis, 24 patients with suppurative arthritis, as observed group; Non suppurative arthritis 32 cases as control group, compared two groups of patients with PCT, ESR and CRP level and the sensitivity and specificity of detection index. Results: the observation group of patients with PCT, ESR and CRP levels are significantly higher than the control group, observation group of PCT, the positive rate in the ESR and CRP were significantly higher than that of control group, P < 0.05, the difference is statistically significant. PCT, ESR and CRP joint detection sensitivity is obvious higher than that of any single indicator detection sensitivity, P < 0.05, the difference is statistically significant. Combined detection specificity and the specificity of the PCT test alone there was no significant difference, P > 0.05, there was no statistically significant difference. Conclusion: PCT, ESR and CRP detection can improve the accuracy of diagnosis of suppurative arthritis, sensitivity and specificity in diagnosis of suppurative arthritis has high clinical value.更多还原