【摘要】 目的探讨西安地区儿童维生素D水平状况,为指导儿童科学合理补充维生素D提供临床依据。方法对2015年3至10月在第四军医大学西京医院儿童保健门诊进行常规检查的487例儿童进行末梢血维生素D水平检测,并对结果进行分析。结果 (1)487例儿童末梢血维生素D总体水平为59.83±26.51nmol/L,不同性别末梢血维生素D水平比较差异无统计学意义(t=0.091,P>0.05);(2)不同年龄组儿童维生素D水平不同,差异有统计学意义(F=2.961,P<0.05),随年龄增长,儿童维生素D水平呈先增高,后降低,再增高趋势;(3)487例儿童末梢血维生素D缺乏总检出率为18.48%(90/487),不同性别儿童维生素D缺乏检出率差异无统计学意义(P>0.05);(4)不同年龄组儿童维生素D缺乏检出率不同,差异有统计学意义(χ2=20.869,P<0.05)。结论婴幼儿期的儿童仍是维生素D缺乏的重点防治对象,同时应加强学龄前期儿童维生素D的摄入和补充。更多还原

【Abstract】 Objective To investigate the levels of vitamin D in children in Xi’an area and to provide clinical guidance for scientific supplementary of vitamin D for children. Methods Vitamin D level in peripheral blood was detected in 487 children receiving routine physical examination in child health care clinic of Xijing Hospital of Fourth Military Medical University from March to October in 2015 and detection results were analyzed. Results Overall level of vitamin D in peripheral blood of 487 children was 59. 83 ± 26. 51nmol/L,and the difference in vitamin D level in peripheral blood between sexes had no significant difference( t = 0. 091,P > 0. 05). Level of vitamin D in children of different age groups was different,and this difference was statistically significant( F = 2. 961,P < 0. 05). With increase of age,level of vitamin D in children presented a trend of increase first,then decrease and then increase again. Overall detection rate of vitamin D deficiency in peripheral blood in 487 children was 18. 48%( 90/487),and there was no statistically significant difference in detection rate of vitamin D deficiency between sexes( P > 0. 05). Deficient rate of vitamin D in different age groups was different,and there was statistically significant difference between groups( χ~2= 20. 869,P < 0. 05). Conclusion Infant and young children are the key objects to prevent vitamin D deficiency,and intake and supplementary of vitamin D should be strengthened for children of preschool age.更多还原