【摘要】 术后电极位置及轨迹信息是脑深部刺激临床疗效评估的有效工具,但是核磁图像中电极伪影严重地影响了术后电极位置的准确估计。该文提出基于核磁图像电极伪影估计术后电极位置的方法,进而确定电极与靶点核团之间的位置关系,有助于明确治疗疗效与电极定位之间的联系,更好地指导外科医生规划最佳植入通路和程控。进行了电极伪影体模实验和分析了10名帕金森病患者脑部核磁图像,结果表明:该方法可以测量电极在丘脑底核中的位置,并具有较小测量误差。更多还原

【Abstract】 The therapeutic benefits are strongly related to the location accuracy of the deep brain stimulation(DBS)electrodes in the target. The postoperative electrode positions cannot be accurately located because of their artifacts.An electrode position estimation method was developed using the artifacts to judge the electrode position relative to the target nucleus to improve the therapeutic effect and the electrode positioning and to help neurosurgeons prepare appropriate surgery plans. Magnetic resonance imaging(MRI)data for artifact locations in a phantom and in 10Parkinson’s disease(PD)patients using a correlation coefficient show that this method can accurately measure the electrode position with a predictable error.更多还原