Objective To investigate the effects of self-developed Xiaodan granules on renal tissue in rat model of kidney failure by pathological morphology analysis. Methods The chronic renal failure rat model was induced by adenine(200mg/kg) for 30 d irrigation. The model rats were randomly divided into model group,as well group of Xiandan granules high and low dose(3.96g/kg,0.99g/kg),and the positive control group(given urine poison granules 2.09g/kg),n=10 foreach. The normal group(n=10) and model groups were given...