【摘要】 采用纸片扩散法对分离自福建省皱纹盘鲍(Haliotis discus hannai)消化道及其养殖水体中的284株异养细菌(其中消化道菌131株,水体菌153株)进行药物敏感测试,以期了解其耐药性概况。结果显示,皱纹盘鲍消化道与养殖水体异养菌对多种抗菌药物的耐药率差异不明显,大部分菌株对青霉素、卡那霉素、庆大霉素、利福平产生耐药性,耐药率最高达83.95%,而对诺氟沙星、恩诺沙星、氯霉素耐药率较低,受试的水体异养菌对诺氟沙星耐药率为0;不同来源菌株的多重耐药(multiple antibiotic resistance,MAR)现象普遍,消化道及其养殖水体异养菌的多重耐药率均值分别为59.15%和51.31%。该研究同时发现相同分离源的菌株对青霉素、卡那霉素、庆大霉素和利福平的耐药率呈现一定的季节波动规律,消化道异养菌于9月耐药率最低,而水体异养菌耐药率在6月最低。结果表明,皱纹盘鲍消化道及水体异养菌的多重耐药率较高,耐药状况较严重。更多还原

【Abstract】 A total of 284 strains(153 were isolated from intestines and 131 were isolated from farming water) were tested by Kirbybauer diffusion method to study the resistance of Haliotis discus hannai in Fujian Province.Results show that many strains resisted penicillin G,kanamycin,gentamicin and rifampin.The resistant rates were up to 83.59%;the resistant rates to norfloxacin,chloramphenicol and enrofloxacin were all relatively low,and resistant rate to norfloxacin was the lowest in farming water.Thus,there is no different resistance between heterotrophic bacteria from intestines and farming water.Multiple antibiotic resistance(MAR) was widespread in different sources and the average MARs were 59.15% and 51.31% in intestines and farming water.The resistant rates to penicillin G,kanamycin,gentamicin and rifampin from intestines were the lowest in September and those from farming water were thelowest in June.更多还原