【摘要】 目的探讨经尿道前列腺等离子剜除术(PKEP)后前列腺癌行腹腔镜下前列腺癌根治术(LRP)的安全性及临床效果。方法回顾性分析自2014年06月至2016年10月在江阴市人民医院泌尿外科行腹腔镜下前列腺癌根治术的55例患者的临床资料,其中13例为行经PKEP而发现前列腺癌(PKEP组),42例由前列腺穿刺而诊断前列腺癌。从42例由前列腺常规穿刺后前列腺癌患者随机抽取13例患者作为非PKEP组,与PKEP组患者的临床特征进行对比研究。结果 PKEP组患者行腹腔镜前列腺癌根治术手术时间[(209.2±46.9)min],长于非PKEP组[(144.6±37.66)min],术中出血[(375.4±251.6)mL],多于非PKEP组[(207.7±122.2)mL]。PKEP组患者发生直肠损伤1例,术后未发生肠瘘。术后均无严重并发症。PKEP组患者与非PKEP组术后尿失禁及术后1个月前列腺特异性抗原(PSA)值无明显差异。结论虽然PKEP手术史给腹腔镜前列腺癌根治术带来了巨大的挑战,但仍旧是安全、可行、有效的。更多还原

【Abstract】 Objective To explore the safety and efficacy of laparoscopic radical prostatectomy(LRP)after plasma kinetic enucleation of prostate(PKEP).Methods The clinical data of 55 cases undergoing LRP in our hospital during Jun.2014 and Oct.2016 were retrospectively analyzed.Of all cases,13 were diagnosed prostate cancer by PKEP(PKEP group),and 42 were diagnosed prostate cancer by prostate biopsy.A total of 13 cases were randomly selected from the 42 patients who were diagnosed prostate cancer by prostate biopsy as non-PKEP group.The clinical features of the two groups were analyzed.ResultsThe mean operation time in PKEP group(209.2±46.9)min was longer than in that in non-PKEP group(144.6±37.66)min.The mean estimated intraoperative blood loss in PKEP group(375.4±251.6)mL was more than that in non-PKEP group(207.7±122.2)mL.Rectal injury occurred in1 case in PKEP group,and no postoperative intestinal fistula happened after operation.No severe complications occurred in the two groups.No significant difference was observed in the incontinence and postoperative PSA between the two groups.Conclusion LRP after PKEP is safe,technically feasible and effective,although it is challenging.更多还原